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GHK-CU (CU50)

$38.00 Original price was: $38.00.$19.99Current price is: $19.99.

50mg/vial *10 vials

GHK-Cu is a naturally occurring tripeptide-copper complex found in human plasma. It functions as a biological regulator that promotes wound healing, stimulates collagen synthesis, and possesses anti-inflammatory and antioxidant properties.

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Description

Buy GHK-Cu Peptide 50mg – Targeted Skin & Hair Regeneration

Support your skin, hair, and recovery routine with GHK-Cu 50mg, a powerful copper peptide known for its rejuvenating and restorative properties.

Designed to work at the cellular level, GHK-Cu helps promote collagen production, improve skin quality, and support healthier hair — making it a versatile option for both aesthetic and recovery-focused goals.

GHK-Cu (glycyl-L-histidyl-L-lysine copper) has emerged as one of the most sought-after peptides in the anti-aging and healing space — and for good reason. Clinical studies report a 17.8% increase in dermal density, a 36% reduction in wrinkle depth, and a 23% improvement in skin elasticity after 12 weeks of consistent use. Add documented wound healing, hair growth promotion, and gene-expression resetting across more than 4,000 genes, and it’s easy to see why demand has exploded.

The problem: explosive demand attracts bad actors. The research peptide market is riddled with underdosed, impure, or outright counterfeit products. Buying the wrong GHK-Cu doesn’t just waste money — it means missing out on the very results that make this peptide worth researching in the first place.

This guide cuts through the noise. We break down exactly what to look for in a vendor, which suppliers are worth your trust in 2026, what you should expect to pay, and the red flags that signal you’re about to get burned.

GHK-Cu (Copper) Peptide

GHK-Cu is a naturally occurring copper-binding peptide composed of 3 amino acids, i.e. glycyl-L-histidyl-L-lysine.(1) -Cu refers to the chemical addition of copper. GHK-Cu (Copper) is a small tripeptide found in plasma and reportedly releases at the time of injury. The concentration of GHK-Cu declines with age. At 20 years, the average concentration of GHK-Cu of 200 ng/mL declines to 80 ng/mL by 60 years.(1)

Studies(4) have suggested when the plasma GHK peptide is added to the cell culture in nanomolar amounts; the peptide has the potential to induce a wide range of responses from growth stimulation to toxic cell differentiation. During the isolation of the peptide, researchers suggested that it exhibited potential chelating properties and might co-isolate with almost the same amount of copper ions and a fifth of the amount of iron found in the cells. When the peptide was incubated in the isolated cells as a bound complex with copper and iron molecules, maximal potential was reported.


Key Benefits

  • 🔹 Promotes collagen production and skin elasticity

  • 🔹 Supports skin repair and rejuvenation

  • 🔹 Helps improve skin tone and texture

  • 🔹 Encourages hair growth and follicle strength

  • 🔹 Aids in tissue recovery and healing


Why Choose 50mg?

The 50mg option provides a balanced approach between potency and flexibility, making it ideal for consistent use without committing to higher quantities.

Perfect for those looking to maintain results or build a structured routine.


Product Highlights

  • ✔ 50mg peptide concentration

  • ✔ Copper peptide complex

  • ✔ High-quality, consistent formulation

  • ✔ Suitable for skin, hair, and recovery support

Why Buy GHK-CU Peptide Online From Synthetic Peptide Lab?

Choosing a reliable supplier is essential for achieving accurate research outcomes. When you buy GHK-CU peptide online from Synthetic Peptide Lab, you gain access to a trusted source focused on quality and transparency.

1. High Purity Standards

Each batch of GHK-CU peptide for sale is produced using advanced synthesis techniques to ensure consistency and reliability.

2. Verified Quality Control

We implement testing procedures to confirm identity and purity, allowing you to confidently buy GHK-CU peptide online.

3. Secure Packaging

Our packaging is designed to preserve peptide stability during storage and transportation.

4. Worldwide Shipping

We deliver to the USA, UK, Canada, Australia, Germany, France, Switzerland, Spain, Portugal, and other European countries, ensuring easy access to GHK-CU peptide for sale globally.


Research Applications of GHK-CU Peptide

GHK-CU peptide is primarily used in laboratory and investigational research environments. Researchers studying peptide interactions and molecular behavior often include it in controlled studies.

When you buy GHK-CU peptide online, it is important to understand:

  • It is intended strictly for research purposes only
  • It is not approved for human consumption
  • It should only be handled by qualified professionals

Maintaining these standards ensures responsible and compliant usage.


Quality Assurance and Manufacturing Process

At Synthetic Peptide Lab, quality is built into every stage of production. Our GHK-CU peptide for sale is developed through:

  • Controlled synthesis environments
  • Advanced manufacturing technologies
  • Strict quality monitoring procedures

This ensures that when customers buy GHK-CU peptide online, they receive a product that meets professional research standards.


How to Buy GHK-CU Peptide Online Safely

If you are planning to buy GHK-CU peptide online, consider the following:

Supplier Transparency

Look for clear product information and testing verification.

Consistency Across Batches

Reliable research depends on uniform product quality.

Secure Delivery

Proper packaging and dependable shipping help maintain product integrity.

Synthetic Peptide Lab makes it simple to buy GHK-CU peptide online for sale with confidence and reliability.


Global Availability and Fast Shipping

We understand the importance of timely delivery in research environments. That’s why we offer:

  • Fast order processing
  • Secure checkout systems
  • Reliable international shipping

No matter your location, accessing GHK-CU peptide for sale is efficient and convenient.


Storage and Handling Guidelines

After you buy GHK-CU peptide online, proper storage is essential:

  • Store in a cool, dry environment
  • Avoid exposure to direct light
  • Follow standard laboratory handling procedures

These steps help preserve stability and product integrity.


Compliance and Responsible Use

All GHK-CU peptide for sale from Synthetic Peptide Lab is distributed under strict compliance standards:

  • Intended for research use only
  • Not marketed for therapeutic or medical purposes
  • Supplied with appropriate handling guidance

This ensures responsible distribution and adherence to industry expectations.


Why Researchers Trust Synthetic Peptide Lab

When professionals choose to buy GHK-CU peptide online, they prioritize reliability, transparency, and consistency. Synthetic Peptide Lab delivers by offering:

  • High-quality research peptides
  • Verified purity and testing
  • Secure ordering systems
  • Responsive customer support

Our commitment ensures that every order of GHK-CU peptide for sale meets the expectations of serious researchers.

GHK Peptide and Metastasis

In this 1983 study,(1) the actions of the mixture of GHK-Cu complex and ascorbic acid (Vitamin C) on the growth of the sarcoma (tumor) cells was observed. 180 mice with cancerous growths were exposed to this mixture. Researchers suggested the mixture had the potential to induce a decline in the growth of carcinogenic cells in the subject mice. It was later reported by the researchers that GHK-Cu peptide complex exhibited some potential in increasing the expression of caspase and the associated genes, as well as gene expression associated with DNA repair. Specifically, this peptide seemed to suppress the growth of two types of cancer cells in experimental settings: SH-SY5Y neuroblastoma cells, which are a model for studying nerve cell behavior and pathology, and U937 histiocytic lymphoma cells, which are used to study the immune system’s response to cancer. Additionally, the peptide might have reactivated the apoptosis pathway, a type of programmed cell death crucial for removing faulty cells, as evidenced by activity in caspases 3 and 7, which are enzymes that play key roles in apoptosis. Conversely, in a study of non-cancerous cells, GHK appeared to promote the growth of NIH-3T3 fibroblasts, which are healthy cells often used as a standard model to examine cell division and growth.

GHK Peptide and Ulcers

This clinical study(10) was carried out in diabetic subjects with neuropathic ulcers. All subjects were enrolled in a standard wound care protocol, where only the subjects with sharp ulcer wound or debridement were entered into this randomized, placebo controlled clinical trial. The study was carried out using GHK-Cu peptide complex gel. All subjects were divided into different groups, where one group was presented with the peptide gel, whereas others were given standard care with a placebo application. Following the study, researchers suggested that the subjects given the gel exhibited apparently elevated healing at 98%+. The gel complex appeared to have the potential to induce closure of 98.5% of plantar ulcers whereas the control only reportedly induced 60.8% of ulcer healing.

GHK Peptide and Behavioral Properties

In this study,(1) GHK-Cu was delivered to mice to measure pain mitigation. Mice were placed on a moderately hot plate. Due to heat and the pain, it would usually take longer for mice to lick their paws; however, upon delivery the peptide, the time taken to lick their paws reduced compared to control environments. Researchers suggested the mice got ‘comfortable’ and their pain was eased faster with the presence of GHK-Cu.

In this study,(11) male rats were deposited into a maze, which was intended to induce anxiety and cause behavioral changes. If anxious, rats were observed to restrict arm movement, keeping “close arms”; whereas “open arm” behavior was shown in rats with lessened levels of anxiety. As a part of the study, once the peptide was delivered, the time spent by the rats in “open arms” state in the maze was monitored. After the study, it was reported by the researchers that the peptide exhibited some potential in increasing “open arms” states in the subjects.

In an additional study,(12) two rats were placed in a small cage and were then given minor electric shocks. As a result of these shocks, the rat would become agitated and attack the second rat. Twelve minutes before this experiment, GHK-Cu peptide was delivered to both rats. It was noted by the researchers that the number of attacks, after the electric shocks, reduced by 5 times than usual.

Specifications

Molecular Formula: C14H23CuN6O4

Molecular Weight: 340.38 g/mol

Sequence: Gly-His-LysCu.xHAc

GHK-Cu Research

GHK-Cu and Skin Cells
GHK-Cu is a natural component of blood and has been studied for its potential impact on dermal regeneration pathways. Research in skin cultures has suggested that GHK may stimulate the synthesis as well as the breaking down of collagen, glycosaminoglycans, and other components of the skin’s extracellular matrix like proteoglycans and chondroitin sulfate. This potential appears to be partially mediated through the positive action of GHK-Cu recruitment on fibroblasts, endothelial cells, and immune cells. The peptide appears to attract these cells to the wound site and coordinates their activity in repairing the damage. The peptide has also been researched for its potential modulation of collagen synthesis. Research in the roles of GHK-Cu suggests its actions may be mediated partially via an expression of transforming growth factor Beta. It is likely that the peptide works through various biochemical pathways and may modify gene expression. Studies in mice suggest that GHK-Cu may increase the rate of wound healing in burns by as much as 33%.[1] The peptide appears to recruit immune cells and fibroblasts to sites of injury and may promote the development of new blood vessels at these sites.

GHK-Cu and Cognitive, Nervous System Functions
The mechanism behind neuronal death, which occurs in degenerative diseases such as Alzheimer’s, is poorly understood. Studies have suggested GHK-Cu’s potential to inhibit loss in neuronal function, which has been associated with such diseases.[2] In these studies, the molecule has been observed to enhance angiogenesis in the nervous system, to potentially stimulate nerve outgrowth, and decrease inflammation in the central nervous system. Further scientific studies support the theory that it may alter the expression profiles of pathological genes and help reset a state of controlled function in dysfunctional systems. Natural GHK-Cu expression is considered to naturally decrease. Some scientists believe that GHK-Cu may possibly exert neuroprotective action against natural insults like gene dysregulation. The peptide has been suggested to protect neurons in rat brains from apoptosis through the well-known miR-339-59/VEGFA pathway, which is considered to become active after brain bleeds and stroke. In the rat models, GHK-Cu was reported to improve the neurological deficits in the brain, reducing swelling and preventing neuronal death associated with over-expression of miR-339-5p.

GHK-Cu and Bacteria
GHK-Cu, in combination with certain fatty acids, may create a potentially antimicrobial compound acting against bacteria and fungi that is considered to interfere with tissue repair processes. Diabetes research has suggested that GHK-Cu may exert such action, with findings reporting a combination of standard procedure and GHK-Cu to induce a 40% increase in wound closure and a 27% reduction in infection rates as opposed to control groups.[3] Similar results have also been noted from studies in ischemic wounds. Researchers report that “GHK-Cu improved healing of ischemic wounds and suppresses inflammation by lowering the level of acute-phase inflammatory cytokines such as TGF-beta and TNF-alpha.”

GHK-Cu and Lungs
Studies in murine models have suggested that GHK-Cu may protect the lungs against fibrosis.[4] The study has also explored the mechanistic action of the peptide. It was observed to modulate TNF-alpha and IL-6 levels, both of which are considered to function as inflammatory molecules and may affect the extracellular matrix and smooth muscles of the lungs. The peptide may reduce lung inflammation, thereby enhancing collagen production and preventing fibrotic remodeling. GHK-Cu was also suggested to be effective in murine research models of acute respiratory distress syndrome (ARDS). This inflammatory lung condition may become aggravated very fast and may be fatal. ARDS is linked with injury and infection. Once again, the suggested underlying mechanism of the peptide action is decreasing the expression of TNF-alpha and IL-6.[5]

In another study, GHK-Cu was investigated for its potential actions on inflammation within a murine model of emphysema induced by cigarette smoke (CS). The experimentation with GHK-Cu appeared to reduce inflammation in the lung tissues of these models. This action was indicated by a decrease in inflammatory cytokines such as IL-1β and TNF-α in the bronchoalveolar lavage fluid, suggesting that GHK-Cu may have an inhibitory action on these proinflammatory markers. Furthermore, the study noted an apparent reduction in myeloperoxidase (MPO) activity, which is primarily found in neutrophils and is an enzyme involved in the model’s response to inflammation. These findings suggest that GHK-Cu might potentially attenuate the inflammatory response triggered by CS exposure. The mechanism behind the potential anti-inflammatory action of GHK-Cu may be associated with its influence on the NF-κB pathway, a key regulator of inflammation. The study observed that GHK-Cu exposure possibly suppresses the activation of NF-κB by modifying the phosphorylation of its inhibitor IκBα, thereby reducing the expression of inflammatory mediators. Additionally, the pre-exposure with GHK-Cu was posited to decrease i-NOS levels through the NF-κB pathway, linking it further to anti-inflammatory processes.[6]

GHK-Cu and Pain Perception
In rat models, the exposure of GHK-Cu was reported to exhibit a concentration-dependent impact on pain-induced behavior. The peptide appeared to deliver analgesic effects mediated through increased levels of the natural painkiller L-lysine.[7] The researchers reported that “It was found the L-lysine residue plays the key role in these effects, because they were observed under the influence of L-lysine [introduction] in [concentrations] close to its equimolar content in the studied tripeptide.” Similar studies have suggested the potential of the peptide to enhance levels of L-arginine, another analgesic amino acid.[8]

GHK-Cu and Oxidative Stress
One research hypothesis suggests that GHK may contribute to reducing the release of iron from ferritin, which catalyzes lipid peroxidation. Specifically, data indicates that GHK may restrict the formation of iron complexes in damaged tissues, potentially reducing inflammation.[9] The proposed mechanism of GHK involves its interaction with the pathways controlling iron release from ferritin, potentially reducing iron release by approximately 87%. This reduction may theoretically lessen inflammation and oxidative stress in impacted tissues. Furthermore, a palmitoylated form of the compound, Pal-GHK, may also decrease the generation of reactive oxygen species and inflammatory cytokines, while potentially enhancing the activity of antioxidant enzymes. In a study conducted using a mouse model, Pal-GHK appeared to inhibit the activation of the Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-κB) and p38 mitogen-activated protein kinase (MAPK) signaling pathways. Both pathways play significant roles in the inflammatory process.[10] NF-κB is a protein complex that functions as a transcription factor, regulating the expression of genes involved in immune and inflammatory responses. The p38 MAPK pathway is considered to be heavily involved in cellular responses to stress and inflammation. Pal-GHK might inhibit p38 MAPK activation by obstructing the upstream kinases that activate this pathway or interfering with the signaling molecules responsible for its phosphorylation. Such inhibition might diminish the inflammatory response, reducing cellular stress. This, in turn, may result in decreased infiltration of inflammatory cells into lung tissues in murine models, alongside lower levels of tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) production, further mitigating tissue damage.

Disclaimer: The products mentioned are not intended for human or animal consumption. Research chemicals are intended solely for laboratory experimentation and/or in-vitro testing. Bodily introduction of any sort is strictly prohibited by law. All purchases are limited to licensed researchers and/or qualified professionals. All information shared in this article is for educational purposes only.

References

  1. Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018 Jul 7;19(7):1987. doi: 10.3390/ijms19071987. PMID: 29986520; PMCID: PMC6073405.
  2. Pickart L, Vasquez-Soltero JM, Margolina A. The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline. Brain Sci. 2017 Feb 15;7(2):20. doi: 10.3390/brainsci7020020. PMID: 28212278; PMCID: PMC5332963.
  3. Pickart L, Vasquez-Soltero JM, Margolina A. The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: implications for cognitive health. Oxid Med Cell Longev. 2012;2012:324832. doi: 10.1155/2012/324832. Epub 2012 May 10. PMID: 22666519; PMCID: PMC3359723.
  4. Zhou XM, Wang GL, Wang XB, Liu L, Zhang Q, Yin Y, Wang QY, Kang J, Hou G. GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1/Smad-Mediated Epithelial-to-Mesenchymal Transition. Front Pharmacol. 2017 Dec 12;8:904. doi: 10.3389/fphar.2017.00904. PMID: 29311918; PMCID: PMC5733019.
  5. Park JR, Lee H, Kim SI, Yang SR. The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice. Oncotarget. 2016 Sep 6;7(36):58405-58417. doi: 10.18632/oncotarget.11168. PMID: 27517151; PMCID: PMC5295439.
  6. Zhang, Q., Yan, L., Lu, J., & Zhou, X. (2022). Glycyl-L-histidyl-L-lysine-Cu2+ attenuates cigarette smoke-induced pulmonary emphysema and inflammation by reducing oxidative stress pathway. Frontiers in molecular biosciences, 9, 925700. https://doi.org/10.3389/fmolb.2022.925700
  7. Sever’yanova LА, Dolgintsev ME. Effects of Tripeptide Gly-His-Lys in Pain-Induced Aggressive-Defensive Behavior in Rats. Bull Exp Biol Med. 2017 Dec;164(2):140-143. doi: 10.1007/s10517-017-3943-3. Epub 2017 Nov 27. PMID: 29181666
  8. Sever’yanova LА, Plotnikov DV. Binding of Glyprolines to L-Arginine Inverts Its Analgesic and Antiagressogenic Effects. Bull Exp Biol Med. 2018 Sep;165(5):621-624. doi: 10.1007/s10517-018-4227-2. Epub 2018 Sep 17. PMID: 30225713
  9. Miller, D. M., DeSilva, D., Pickart, L., & Aust, S. D. (1990). Effects of glycyl-histidyl-lysyl chelated Cu(II) on ferritin dependent lipid peroxidation. Advances in experimental medicine and biology, 264, 79–84. https://doi.org/10.1007/978-1-4684-5730-8_11
  10. Sakuma, S., Ishimura, M., Yuba, Y., Itoh, Y., & Fujimoto, Y. (2018). The peptide glycyl-ʟ-histidyl-ʟ-lysine is an endogenous antioxidant in living organisms, possibly by diminishing hydroxyl and peroxyl radicals. International journal of physiology, pathophysiology and pharmacology, 10(3), 132–138.
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This product is strictly for research/laboratory use only. Human or animal use and/or consumption is strictly prohibited by law. Only qualified and licensed professionals should handle these products. Any information found on Biotech Peptides is strictly for educational purposes only. Refer to our terms and conditions for more details.

Important Note

For best results, use consistently as part of a routine. Outcomes may vary depending on application, lifestyle, and individual factors.

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